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microarray raw data files  (Biotechnology Information)

 
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    Biotechnology Information microarray raw data files
    Microarray Raw Data Files, supplied by Biotechnology Information, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/microarray+raw+files/microarray+data+files/pm32755720-75-3-14
    Average 90 stars, based on 1 article reviews
    microarray raw data files - by Bioz Stars, 2026-09
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    Related Articles

    Microarray:

    Article Title: Synergistic drug interactions of the histone deacetylase inhibitor givinostat (ITF2357) in CRLF2-rearranged pediatric B-cell precursor acute lymphoblastic leukemia identified by high-throughput drug screening
    Article Snippet: .. All microarray raw data (CEL files) and probe set signals are available at the National Center for Biotechnology Information Gene Expression Omnibus database (GEO, http://www.ncbi.nlm.nih.gov/geo/ ), series accession number GSE77270 ( http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?token=mdwpqoeqhjuhzef&acc=GSE77270 ) [ ]. ..

    Article Title: Dedifferentiation and neuronal repression define familial Alzheimer’s disease
    Article Snippet: .. Microarray data corresponding to NDC and PSEN1 mutation EOFAD human brain samples from a previously published study ( ) were retrieved from the National Center for Biotechnology Information (NCBI) GEO database (GSE39420) as raw CEL intensity files. ..

    Article Title: Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche
    Article Snippet: .. Microarray raw data (cel files) and processed data have been deposited in the National Center for Biotechnology Information (NCBI)’s Gene Expression Omnibus and are accessible through GEO Series accession number GSE123710. .. All in vitro data were analysed using Student’s t-test with GraphPadPrism 6 statistical software (GraphPad Software Inc).

    Article Title: The influence of orexin B on the transcriptome profile of porcine myometrial explants during early implantation.
    Article Snippet: This study aimed to determine the effect of orexin B (OXB) on the global expression pattern and the relationships among differentially expressed genes (DE-genes) in the transcriptome of myometrial explants during the early implantation period in the pig (day 15 of pregnancy).. The changes in the transcriptome profile of the porcine myometrium were investigated using the Porcine (V2) Two-colour Gene Expression Microarray, 4 44.. An analysis of the data from the microarray experiment revealed that 1540 DE-genes were affected by OXB, of which 1135 exhibited fold changes (FC) greater than 1.2 (P < 0.05).

    Article Title: Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells.
    Article Snippet: Proteinase-activated receptors (PARs) are G protein-coupled receptors (GPCRs) activated by limited N-terminal proteolysis.. PARs are highly expressed in many cancer cells, including prostate cancer (PCa), and regulate various aspects of tumor growth and metastasis.. Specific activators of PARs in different physiological and pathophysiological contexts remain poorly defined.

    Article Title: Dedifferentiation and neuronal repression define familial Alzheimer's disease.
    Article Snippet: .. Human brain transcriptomic analysis Microarray data corresponding to NDC and PSEN1 mutation EOFAD human brain samples from a previously published study (58) were retrieved from the National Center for Biotechnology Information (NCBI) GEO database (GSE39420) as raw CEL intensity files. ..

    Article Title: Up-regulation of EP 2 and EP 3 receptors in human tolerogenic dendritic cells boosts the immunosuppressive activity of PGE 2 .
    Article Snippet: .. Microarray raw data (.cel files) and processed data have been uploaded in the Gene Expression Omnibus of the National Center for Biotechnology Information (Bethesda, MD, USA) and are accessible through GEO series accession number GSE56017. .. Total RNA was isolated with RNeasy Mini Kit columns (Qiagen, Hilden, Germany).

    Gene Expression:

    Article Title: Synergistic drug interactions of the histone deacetylase inhibitor givinostat (ITF2357) in CRLF2-rearranged pediatric B-cell precursor acute lymphoblastic leukemia identified by high-throughput drug screening
    Article Snippet: .. All microarray raw data (CEL files) and probe set signals are available at the National Center for Biotechnology Information Gene Expression Omnibus database (GEO, http://www.ncbi.nlm.nih.gov/geo/ ), series accession number GSE77270 ( http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?token=mdwpqoeqhjuhzef&acc=GSE77270 ) [ ]. ..

    Article Title: Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche
    Article Snippet: .. Microarray raw data (cel files) and processed data have been deposited in the National Center for Biotechnology Information (NCBI)’s Gene Expression Omnibus and are accessible through GEO Series accession number GSE123710. .. All in vitro data were analysed using Student’s t-test with GraphPadPrism 6 statistical software (GraphPad Software Inc).

    Article Title: The influence of orexin B on the transcriptome profile of porcine myometrial explants during early implantation.
    Article Snippet: This study aimed to determine the effect of orexin B (OXB) on the global expression pattern and the relationships among differentially expressed genes (DE-genes) in the transcriptome of myometrial explants during the early implantation period in the pig (day 15 of pregnancy).. The changes in the transcriptome profile of the porcine myometrium were investigated using the Porcine (V2) Two-colour Gene Expression Microarray, 4 44.. An analysis of the data from the microarray experiment revealed that 1540 DE-genes were affected by OXB, of which 1135 exhibited fold changes (FC) greater than 1.2 (P < 0.05).

    Article Title: Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells.
    Article Snippet: Proteinase-activated receptors (PARs) are G protein-coupled receptors (GPCRs) activated by limited N-terminal proteolysis.. PARs are highly expressed in many cancer cells, including prostate cancer (PCa), and regulate various aspects of tumor growth and metastasis.. Specific activators of PARs in different physiological and pathophysiological contexts remain poorly defined.

    Article Title: Up-regulation of EP 2 and EP 3 receptors in human tolerogenic dendritic cells boosts the immunosuppressive activity of PGE 2 .
    Article Snippet: .. Microarray raw data (.cel files) and processed data have been uploaded in the Gene Expression Omnibus of the National Center for Biotechnology Information (Bethesda, MD, USA) and are accessible through GEO series accession number GSE56017. .. Total RNA was isolated with RNeasy Mini Kit columns (Qiagen, Hilden, Germany).

    Mutagenesis:

    Article Title: Dedifferentiation and neuronal repression define familial Alzheimer’s disease
    Article Snippet: .. Microarray data corresponding to NDC and PSEN1 mutation EOFAD human brain samples from a previously published study ( ) were retrieved from the National Center for Biotechnology Information (NCBI) GEO database (GSE39420) as raw CEL intensity files. ..

    Article Title: Dedifferentiation and neuronal repression define familial Alzheimer's disease.
    Article Snippet: .. Human brain transcriptomic analysis Microarray data corresponding to NDC and PSEN1 mutation EOFAD human brain samples from a previously published study (58) were retrieved from the National Center for Biotechnology Information (NCBI) GEO database (GSE39420) as raw CEL intensity files. ..

    other:

    Article Title: Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche
    Article Snippet: • Submission of methodologic details to EV-TRACK (evtrack.org) with EV-TRACK number provided (strongly encouraged) • Submission of data (proteomic, sequencing, other) to relevant public, curated databases or open- access repositories Microarray raw data [.cel files] and processed data have been deposited in the National Center for Biotechnology Information [NCBI] ’s Gene Expression Omnibus and are accessible through GEO Series accession number GSE123710.



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    Image Search Results


    Gene expression dataset . A) The gene expression dataset analyzed comprises cell samples from different levels of myeloid differentiation process (stem/progenitor cells, precursors and terminally differentiated cells). The graph describes relationships between the cellular contexts analyzed within myeloid differentiation tree. For each cell type, the number of samples examined with independent microarray experiments is indicated in brackets. B) Dendrogram obtained by unsupervised hierarchical clustering on gene expression data matrix. Pearson correlation and average were used as similarity measure and linking method, respectively.

    Journal: BMC Genomics

    Article Title: Genomic expression during human myelopoiesis

    doi: 10.1186/1471-2164-8-264

    Figure Lengend Snippet: Gene expression dataset . A) The gene expression dataset analyzed comprises cell samples from different levels of myeloid differentiation process (stem/progenitor cells, precursors and terminally differentiated cells). The graph describes relationships between the cellular contexts analyzed within myeloid differentiation tree. For each cell type, the number of samples examined with independent microarray experiments is indicated in brackets. B) Dendrogram obtained by unsupervised hierarchical clustering on gene expression data matrix. Pearson correlation and average were used as similarity measure and linking method, respectively.

    Article Snippet: In particular, raw microarray data (Affymetrix .CEL files) were obtained for a total of 24 samples from 8 different cell types of all myelopoietic lineages, representing a reference dataset for a comprehensive analysis of genomic expression during cell differentiation.

    Techniques: Expressing, Microarray

    Genetic deletion of SphK1 reduced CLDN2 in HER2/neu-induced mice breast tumors. (A) Whole genome expression profile evaluated by microarray analysis assessed the expression of 39000 gene transcripts. Gene expression microarray heatmap (n = 2 per group) of dysregulated genes. (B) Twenty molecules with the most significant expression changes (10 up-regulation and 20 down-regulation) between SphK1+/+ and SphK1−/− tumors are shown. (C) CLDN2 mRNA expression in tumors from SphK1+/+ and SphK1−/− mice was confirmed by qRT-PCR analysis and analyzed by unpaired t-test. ****P ≤ 0.0001 vs. SphK1+/+. (D) Representative paraffin-tumor sections immunostained for CLDN2 in tumors from SphK1+/+ and SphK1−/− mice (P = 0.1339).

    Journal: Carcinogenesis

    Article Title: Genetic deletion of sphingosine kinase 1 suppresses mouse breast tumor development in an HER2 transgenic model

    doi: 10.1093/carcin/bgx097

    Figure Lengend Snippet: Genetic deletion of SphK1 reduced CLDN2 in HER2/neu-induced mice breast tumors. (A) Whole genome expression profile evaluated by microarray analysis assessed the expression of 39000 gene transcripts. Gene expression microarray heatmap (n = 2 per group) of dysregulated genes. (B) Twenty molecules with the most significant expression changes (10 up-regulation and 20 down-regulation) between SphK1+/+ and SphK1−/− tumors are shown. (C) CLDN2 mRNA expression in tumors from SphK1+/+ and SphK1−/− mice was confirmed by qRT-PCR analysis and analyzed by unpaired t-test. ****P ≤ 0.0001 vs. SphK1+/+. (D) Representative paraffin-tumor sections immunostained for CLDN2 in tumors from SphK1+/+ and SphK1−/− mice (P = 0.1339).

    Article Snippet: Partek pre-processes raw intensity files from microarray experiment using GCRMA’s background subtraction and uses quantile normalization as the normalization technique.

    Techniques: Expressing, Microarray, Gene Expression, Quantitative RT-PCR

    SphK1 and CLDN2 levels are increased in HER2-positive breast cancers in humans. Tissue microarray containing breast cancer samples from 92 HER2-positive breast cancer patients and matched adjacent normal breast tissues (n = 34) are stained for SphK1 and CLDN2. Staining were scored based on the intensity (0–3) and proportion (0–3), and the total scores were used for the analysis. [(A) and (B)] SphK1 and CLDN2 expressions were compared with pathological features including grade, stage and hormone receptor status. [(C) and (D)] Representative image of high, moderate and low SphK1 and CLDN2 expressing tumors.

    Journal: Carcinogenesis

    Article Title: Genetic deletion of sphingosine kinase 1 suppresses mouse breast tumor development in an HER2 transgenic model

    doi: 10.1093/carcin/bgx097

    Figure Lengend Snippet: SphK1 and CLDN2 levels are increased in HER2-positive breast cancers in humans. Tissue microarray containing breast cancer samples from 92 HER2-positive breast cancer patients and matched adjacent normal breast tissues (n = 34) are stained for SphK1 and CLDN2. Staining were scored based on the intensity (0–3) and proportion (0–3), and the total scores were used for the analysis. [(A) and (B)] SphK1 and CLDN2 expressions were compared with pathological features including grade, stage and hormone receptor status. [(C) and (D)] Representative image of high, moderate and low SphK1 and CLDN2 expressing tumors.

    Article Snippet: Partek pre-processes raw intensity files from microarray experiment using GCRMA’s background subtraction and uses quantile normalization as the normalization technique.

    Techniques: Microarray, Staining, Expressing